1233324-44-1

Basic information

• Product Name: 5-bromopentyl formate
• Synonyms: 5-bromopentyl formate
• CAS NO: 1233324-44-1
• Molecular Weight: 195.056
• Mol File: 1233324-44-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromopentyl formate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromopentyl formate(1233324-44-1)
• EPA Substance Registry System: 5-bromopentyl formate(1233324-44-1)

Safety Data

• Hazardous Substances Data: 1233324-44-1(Hazardous Substances Data)

Upstream product

• 57978-00-4 6-bromohexanal 

Relevant articles and documents

Hypervalent λ3-bromane strategy for Baeyer-Villiger oxidation: Selective transformation of primary aliphatic and aromatic aldehydes to formates, which is missing in the classical Baeyer-Villiger oxidation

A conceptually distinct, modern strategy for Baeyer-Villiger oxidation (BVO) was developed. Our novel method involves initial hydration of water to carbonyl compounds, followed by ligand exchange of hypervalent aryl-λ3-bromane on bromane(III) with the resulting hydrate, yielding a new type of activated Criegee intermediate. The intermediate undergoes BV rearrangement and produces an ester via facile reductive elimination of an aryl-λ3-bromanyl group, because of the hypernucleofugality. The novel strategy makes it possible to induce selectively the BV rearrangement of straight chain primary aliphatic as well as aromatic aldehydes, which is missing in the classical BVO: for instance, octanal and benzaldehyde afforded rearranged formate esters with high selectivity (>95%) under our conditions, while the attempted classical BVO produced only carboxylic acids. This firmly establishes the powerful nature of new methodology for BVO.