1233335-57-3

Basic information

• Product Name: methyl 6,8-bis(tert-butoxycarbonylamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxylate
• Synonyms: methyl 6,8-bis(tert-butoxycarbonylamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxylate
• CAS NO: 1233335-57-3
• Molecular Weight: 458.471
• Mol File: 1233335-57-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 6,8-bis(tert-butoxycarbonylamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 6,8-bis(tert-butoxycarbonylamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxylate(1233335-57-3)
• EPA Substance Registry System: methyl 6,8-bis(tert-butoxycarbonylamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxylate(1233335-57-3)

Safety Data

• Hazardous Substances Data: 1233335-57-3(Hazardous Substances Data)

Upstream product

• 1233335-56-2 di-tert-butyl (4,6-diamino-1,3-phenylene)dicarbamate 
• 38256-25-6 dimethyl (E)-2-oxoglutaconate 

Relevant articles and documents

Efficient total synthesis of ammosamide B

A total synthesis of ammosamide B, a metabolite of the marine-derived Streptomyces strain CNR-698, has been executed in nine steps and 6.9% overall yield. The key step involves the condensation of a 4,6-diBoc-protected 1,3,4,6-tetraaminobenzene derivative with dimethyl 2-ketoglutaconate, which effectively constructs the pyrrolidinone ring and the quinoline ring in a single step. This contributes a unique approach to the synthesis of pyrroloquinoline alkaloids that offers the advantages of brevity and relatively high overall yield.