123336-38-9Relevant academic research and scientific papers
Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors.
Kalgutkar, Amit S,Rowlinson, Scott W,Crews, Brenda C,Marnett, Lawrence J
, p. 521 - 524 (2002)
This paper describes SAR studies involved in the transformation of the NSAID meclofenamic acid into potent and selective cyclooxygenase-2 (COX-2) inhibitors via neutralization of the carboxylate moiety in this nonselective COX inhibitor.
FENAMIC ACID HYDROXAMATE DERIVATIVES HAVING CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITION
-
, (2008/06/13)
The present invention is novel selected hydroxamic acid derivatives of fenamic acids having 5-lipoxygenase and cyclooxygenase inhibiting properties, pharmaceutical compositions for treating conditions advantageously affected by the inhibition and methods
