1233390-40-3Relevant academic research and scientific papers
Efficient construction of functionalized 5-carboxymethyl tetramic acids using N-Ac-l-aspartic anhydride as chiral building block
Prousis, Kyriakos C.,Markopoulos, John,Mckee, Vickie,Igglessi-Markopoulou, Olga
experimental part, p. 3944 - 3950 (2010/07/04)
A novel method for the synthesis of densely functionalized optically active 5-carboxymethyl tetramic acids is reported. The proposed strategy is focused on the synthesis of 3,3′-disubstituted pyrrolidine-2,4-diones as useful molecules for the synthesis of natural products. The proposed methodology has been established by X-ray diffraction structure analysis.
