123345-52-8Relevant academic research and scientific papers
New cycloalkylpyrazoles as potential cyclooxygenase inhibitors
Cardia,Corda,Fadda,Maccioni,Maccioni,Plumitallo
, p. 698 - 708 (2007/10/03)
In this study some cycloalkyl-3-(N-substituted carbamoyl)-1-phenylpyrazoles have been synthesized in order to screen their capability to inhibit human cyclooxygenase. The synthetic pathway is based on the well known property of nitrilimines to undergo 1,3-dipolar cycloaddition reactions. The structures of all the synthesized compounds have been elucidated by means of both analytical and spectroscopic methods.
