123345-90-4

Upstream product

• 18841-76-4 D-galactose phenylhydrazone 
• 123345-89-1 4,5,6,7-Tetrahydro-1-phenyl-1H-indazole-3-methanol 
• 2562-37-0 1-nitrocyclohexene 

Downstream Products

• 32275-63-1 4,5,6,7-tetrahydro-1-phenyl-1H-indazole-3-carboxylic acid 
• 123345-27-7 5-(4,5,6,7-Tetrahydro-1-phenyl-1H-indazol-3-yl)-(Z)-4-pentenoic acid 

Relevant academic research and scientific papers

REACTION OF D-GALACTOSE PHENYLHYDRAZONE WITH NITROALKENES:SYNTHESIS OF PENTAHYDROXYPENTYLPYRAZOLES

D-Galactose phenylhydrazone reacts with 1- and 2-substituted and 1,2-disubstituted nitroalkenes, with loss of the nitro group, to give moderate yields of 3-(D-galacto-pentitol-1-yl)-1-phenylpyrazoles variously substituted at positins 4, 5 and a mechanism is proposed.Acetylation of these products affords pentaacetates and periodate oxidation gave the corresponding 1-phenylpyrazole-3-carbaldehyde derivatives, some of which were oxidised to the carboxylic acids.U.v., i.r., and n.m.r. data confirm the proposed structures.

Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents

The present invention provides novel compositions of matter and their therapeutic applications. More particularly, the present invention consists of novel cyclopentapyrazole and tetrahydroindazole compounds of formula XXX and their use as antiallergy agents, antiinflammatory agents or intermediates. STR1