123348-27-6

Basic information

• Product Name: 2-Bromo-7-iodo-9H-fluoren
• Synonyms: 2-Bromo-7-iodo-9H-fluoren;2-BroMo-7-iodofluorene;9H-Fluorene, 2-broMo-7-iodo-;2-BroMo-7-iodo-9H-fluorene;2-broMine-7-iodinefluorene;2-bromo-7-iodo-fluoren
• CAS NO: 123348-27-6
• Molecular Formula: C₁₃H₈BrI
• Molecular Weight: 371.01109
• EINECS: 1592732-453-0
• Mol File: 123348-27-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 178-180℃
• Boiling Point: 426.5±38.0 °C(Predicted)
• Appearance: /
• Density: 1.988±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Toluene
• CAS DataBase Reference: 2-Bromo-7-iodo-9H-fluoren(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-7-iodo-9H-fluoren(123348-27-6)
• EPA Substance Registry System: 2-Bromo-7-iodo-9H-fluoren(123348-27-6)

Safety Data

• Hazardous Substances Data: 123348-27-6(Hazardous Substances Data)

Usage

Uses

2-Bromo-7-iodofluorene is mainly used as intermediate of Ledipasvir. Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion.

Upstream product

• 2523-42-4 2-iodo-9H-fluorene 
• 6638-60-4 2-amino-7-bromofluorene 

Downstream Products

• 1352172-27-0 C₂₁H₁₂BrNO₂ 
• 1352172-20-3 2-{[m,p-didodecyloxyphenyl]ethynyl}-7-[(p-nitrophenyl)ethynyl]fluorene 
• 1352172-29-2 C₂₂H₁₂BrN 
• 1352172-22-5 p-[(2-{[m,p-didodecyloxyphenyl]ethynyl}-7-fluorenyl)ethynyl]benzonitrile 
• 1352172-28-1 C₂₂H₁₃BrO 
• 1352172-21-4 p-[(2-{[m,p-didodecyloxyphenyl]ethynyl}-7-fluorenyl)ethynyl]benzaldehyde 
• 867374-53-6 2-bromo-7-iodo-9H-fluoren-9-one 

Relevant articles and documents

One-photon photophysics and two-photon absorption of 4-[9,9-Di(2- ethylhexyl)-7-diphenylaminofluoren-2-yl]-2,2′:6′, 2″-terpyridine and their platinum chloride complexes

The synthesis, one-photon photophysics and two-photon absorption (2PA) of three dipolar D-π-A 4-[9,9-di(2-ethylhexyl)-7-diphenylaminofluoren-2-yl]-2, 2′:6′,2″-terpyridine and their platinum chloride complexes with different linkers between the donor and acceptor are reported. All ligands exhibit 1π,π* transition in the UV and 1π,π*/1ICT (intramolecular charge transfer) transition in the visible regions, while the complexes display a lower-energy 1π,π*/1CT (charge transfer) transition in the visible region in addition to the high-energy 1π,π* transitions. All ligands and the complexes are emissive at room temperature and 77 K, with the emitting excited state assigned as the mixed 1π, π* and 1CT states at RT. Transient absorption from the ligands and the complexes were observed. 2PA was investigated for all ligands and complexes. The two-photon absorption cross-sections (θ2) of the complexes (600-2000 GM) measured by Z-scan experiment are much larger than those of their corresponding ligands measured by the two-photon induced fluorescence method. The ligand and the complex with the ethynylene linker show much stronger 2PA than those with the vinylene linker.