1233481-72-5Relevant academic research and scientific papers
A concise enantioselective total synthesis of (+)-epi-muricatacin, using asymmetric hydrogenation/intramolecular iodoetherification as key steps
Kumaraswamy, Gullapalli,Ramakrishna, Duggirala,Santhakumar, Kondapalli
, p. 544 - 548 (2010)
A concise enantioselective total synthesis of (+)-epi-muricatacin, a potent cytotoxic agent, is described. A key feature of this protocol is a catalytic asymmetric hydrogenation and a chiral auxiliary mediated intramolecular iodoetherification to ensure a high degree of distereo- and enantiocontrol.
