1233497-01-2

Basic information

• Product Name: C₁₉H₁₃Cl₂NO₂
• CAS NO: 1233497-01-2
• Molecular Weight: 358.224
• Mol File: 1233497-01-2.mol

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₃Cl₂NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₃Cl₂NO₂(1233497-01-2)
• EPA Substance Registry System: C₁₉H₁₃Cl₂NO₂(1233497-01-2)

Safety Data

• Hazardous Substances Data: 1233497-01-2(Hazardous Substances Data)

Relevant articles and documents

Structure-activity relationship (SAR) investigations of tetrahydroquinolines as BKCa agonists

The membrane bound large-conductance, calcium-activated potassium channel (BKCa) is an important regulator of neuronal activity. Here we describe the identification and structure-activity relationship of a novel class of potent tetrahydroquinoline BKCa agonists. An example from this class of BKCa agonists was shown to depress the spontaneous neuronal discharges in an electrophysiological model of migraine.