1233516-74-9Relevant academic research and scientific papers
One-pot synthesis of pyrimido[1,6-a ]indol-1(2 H)-one derivatives by a nucleophilic addition/Cu-catalyzed N-arylation/Pd-catalyzed C-H activation sequential process
Wang, Zhi-Jing,Yang, Jian-Guo,Yang, Fan,Bao, Weiliang
supporting information; experimental part, p. 3034 - 3037 (2010/09/05)
A novel and convenient one-pot synthesis of pyrimido[1,6-a]indol-1(2H)-one derivatives through a nucleophilic addition/Cu-catalyzed N-arylation/Pd- catalyzed C-H activation sequential process is described. The reaction of easily prepared ortho-gem-dibromovinyl isocyanates with N-alkyl-anilines gave the desired indole derivatives in moderate to good yields.
