123358-92-9

Upstream product

• 563-79-1 2,3-Dimethyl-2-butene 
• 696-63-9 4-Methoxybenzenethiol 

Downstream Products

• 123358-93-0 3-(4-Methoxy-phenylsulfanylmethyl)-2-methyl-but-3-en-2-yl-hydroperoxide 
• 123358-94-1 (S)-1-(4-Methoxy-phenylsulfanyl)-2,3-dimethyl-but-3-en-2-yl-hydroperoxide 
• 123358-96-3 3-(4-Methoxy-phenylsulfanylmethyl)-2-methyl-but-3-en-2-ol 
• 123358-99-6 (S)-1-(4-Methoxy-phenylsulfanyl)-2,3-dimethyl-but-3-en-2-ol 
• 114597-52-3 1-<4-(methoxyphenyl)sulfinyl>-2,3-dimethyl-2-butene 

Relevant academic research and scientific papers

Direct Allylic C(sp3)?H and Vinylic C(sp2)?H Thiolation with Hydrogen Evolution by Quantum Dots and Visible Light

Direct allylic C?H thiolation is straightforward for allylic C(sp3)?S bond formation. However, strong interactions between thiol and transition metal catalysts lead to deactivation of the catalytic cycle or oxidation of sulfur atom under oxidative condition. Thus, direct allylic C(sp3)?H thiolation has proved difficult. Represented herein is an exceptional for direct, efficient, atom- and step-economic thiolation of allylic C(sp3)?H and thiol S?H under visible light irradiation. Radical trapping experiments and electron paramagnetic resonance (EPR) spectroscopy identified the allylic radical and thiyl radical generated on the surface of photocatalyst quantum dots (QDs). The C?S bond formation does not require external oxidants and radical initiators, and hydrogen (H2) is produced as byproduct. When vinylic C(sp2)?H was used instead of allylic C(sp3)?H bond, the radical-radical cross-coupling of C(sp2)?H and S?H was achieved with liberation of H2. Such a unique transformation opens up a door toward direct C?H and S?H coupling for valuable organosulfur chemistry.