1233582-98-3Relevant academic research and scientific papers
Chiral 1-phenylethylamine-derived phosphine-phosphoramidite ligands for highly enantioselective Rh-catalyzed hydrogenation of β-(acylamino) acrylates: Significant effect of substituents on 3,3′-positions of binaphthyl moiety
Zhou, Xiao-Mao,Huang, Jia-Di,Luo, Li-Bin,Zhang, Chen-Lu,Hu, Xiang-Ping,Zheng, Zhuo
, p. 2320 - 2322 (2010)
A series of new chiral phosphine-phosphoramidite ligands with a 3,3′-substituted binaphthyl moiety were prepared from 1-phenylethylamine, and successfully applied in the Rh-catalyzed asymmetric hydrogenation of β-(acylamino)acrylates. The research disclosed that the substituents on the 3,3′-positions of binaphthyl moiety significantly influenced the enantioselectivity.
