1233713-00-2Relevant academic research and scientific papers
C-H Functionalization via Remote Hydride Elimination: Palladium Catalyzed Dehydrogenation of ortho-Acyl Phenols to Flavonoids
Zhao, Xiaomei,Zhou, Jiabin,Lin, Shuying,Jin, Xukang,Liu, Renhua
, p. 976 - 979 (2017/03/14)
Although deprotonation of electron-poor C-H bonds to carbon anions with bases has long been known and widely used in organic synthesis, the hydride elimination from electron-rich C-H bonds to carbon cations or partial carbocations for the introduction of nucleophiles is a comparatively less explored area. Here we report that the carbonyl β-C(sp3)-H bond hydrogens of ortho-acyl phenols could be substituted by intramolecular phenolic hydroxyls to form O-heterocycles, followed by dehydrogenation of the O-heterocycle into flavonoids. The cascade reaction is catalyzed by Pd/C without added oxidants and sacrificing hydrogen acceptors.
Synthesis of 3-methylflavones and their antioxidant and antibacterial activities
Jayashree, B. S.,Alam, Afroze,Vijay Kumar, D.,Nayak, Yogendra
, p. 1991 - 1996,6 (2020/07/30)
An attempt was made to synthesise newer 3-methylflavones with various substitution on the ring A and B of 2-phenylchromen-4-one. They were evaluated for antioxidant activity and antibacterial activity against the Gram-positive and Gram-negative bacteria.
Antioxidant and antibacterial activity of new 3-methylflavones
Jayashree,Alam, Afroze,Kumar, D. Vijay,Nayak, Yogendra
, p. 237 - 240 (2011/12/15)
Synthesis of new 3-methylflavones with various substitution on the ring A and B is being described. They were evaluated for antioxidant and antibacterial activity against Gram positive and Gram negative bacteria. Test compounds such as F-4,9,11,12 and 20
