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(1H-1,2,4-triazol-3-yl)Methanol is a synthetic intermediate with a unique chemical structure that features a 1H-1,2,4-triazole ring and a hydroxymethyl group. (1H-1,2,4-triazol-3-yl)Methanol plays a significant role in the synthesis of various pharmaceutical agents and has potential applications in the development of new drugs.

123372-69-0

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123372-69-0 Usage

Uses

Used in Pharmaceutical Synthesis:
(1H-1,2,4-triazol-3-yl)Methanol is used as a synthetic intermediate for the preparation of heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists. These antagonists are important in the development of drugs targeting acid-related disorders, such as gastroesophageal reflux disease (GERD) and peptic ulcers.
Used in Neuropharmacology:
(1H-1,2,4-triazol-3-yl)Methanol is also utilized in the synthesis of GABAA receptor agonists at the α3 subunit. GABAA receptors are ligand-gated chloride channels that play a crucial role in inhibiting neuronal excitability in the central nervous system. Agonists targeting the α3 subunit have potential applications in the treatment of various conditions, such as insomnia, anxiety, and alcohol dependence, by modulating the activity of these receptors.

Check Digit Verification of cas no

The CAS Registry Mumber 123372-69-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,3,7 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 123372-69:
(8*1)+(7*2)+(6*3)+(5*3)+(4*7)+(3*2)+(2*6)+(1*9)=110
110 % 10 = 0
So 123372-69-0 is a valid CAS Registry Number.

123372-69-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1H-1,2,4-Triazol-5-ylmethanol

1.2 Other means of identification

Product number -
Other names 3-Hydroxymethyl-1,2,4-triazol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123372-69-0 SDS

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