1233843-43-0

Basic information

• Product Name: (-)-(S)-2-amino-N-((1R,2R,3R,5R)-3-(6-(dimethylamino)-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentyl)-3-(4-methoxyphenyl)propanamide
• Synonyms: (-)-(S)-2-amino-N-((1R,2R,3R,5R)-3-(6-(dimethylamino)-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentyl)-3-(4-methoxyphenyl)propanamide
• CAS NO: 1233843-43-0
• Molecular Weight: 603.678
• Mol File: 1233843-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(S)-2-amino-N-((1R,2R,3R,5R)-3-(6-(dimethylamino)-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentyl)-3-(4-methoxyphenyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(S)-2-amino-N-((1R,2R,3R,5R)-3-(6-(dimethylamino)-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentyl)-3-(4-methoxyphenyl)propanamide(1233843-43-0)
• EPA Substance Registry System: (-)-(S)-2-amino-N-((1R,2R,3R,5R)-3-(6-(dimethylamino)-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentyl)-3-(4-methoxyphenyl)propanamide(1233843-43-0)

Safety Data

• Hazardous Substances Data: 1233843-43-0(Hazardous Substances Data)

Upstream product

• 1233843-25-8 (-)-(1R,2R,3R,5R)-2-amino-5-(6-(dimethylamino)-9H-purin-9-yl)-3-(hydroxymethyl)-cyclopentanol 
• 17554-34-6 (2S)-2-[(benzyloxycarbonyl)amino]-3-(4-methoxyphenyl)propanoic acid 

Downstream Products

• 1233843-28-1 (-)-(S)-2-amino-N-((1R,2R,3R,5R)-3-(6-(dimethylamino)-9H-purin-9-yl)-2-hydroxy-5-(hydroxymethyl)cyclopentyl)-3-(4-methoxyphenyl)propanamide 

Relevant articles and documents

Syntheses of carbocyclic aminonucleosides and (-)-epi-4′-carbocyclic puromycin: application of palladium(0)/indium iodide-allylations and tethered aminohydroxylations

Carbocyclic aminonucleosides and epi-4′-carbocyclic puromycin were prepared from an acylnitroso-derived hetero Diels-Alder cycloadduct. Pd(0)/InI-mediated allylations of a formyl species were used to install the 4′-hydroxymethyl group. A tethered aminohydroxylation strategy was employed to install the cis-2′,3′-aminoalcohol moiety with complete regio- and diastereocontrol.