123387-57-5Relevant academic research and scientific papers
Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2. 1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors
Nagase, Tsuyoshi,Takahashi, Toshiyuki,Sasaki, Takahide,Nagumo, Akira,Shimamura, Ken,Miyamoto, Yasuhisa,Kitazawa, Hidefumi,Kanesaka, Maki,Yoshimoto, Ryo,Aragane, Katsumi,Tokita, Shigeru,Sato, Nagaaki
supporting information; experimental part, p. 4111 - 4114 (2010/02/17)
Long chain fatty acid elongase 6 (ELOVL6) catalyzes the elongation of long chain fatty acyl-CoAs and is a potential target for the treatment of metabolic disorders. The ultrahigh throughput screen of our corporate chemical collections resulted in the iden
α-LITHIOAMINE SYNTHETIC EQUIVALENTS FROM DIPOLE-STABILIZED CARBANIONS: THE t-BOC GROUP AS AN ACTIVATOR FOR α'-LITHIATION OF CARBAMATES
Beak, Peter,Lee, Won-Koo
, p. 1197 - 1200 (2007/10/02)
The t-Boc group activates the α'-lithiation of piperidinyl and related carbamates to give lithium reagents which add to electrophiles to provide α'-elaborated carbamates.
