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1-(4-tolyl)-2-(trifluoromethyl)-1H-indole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1233881-82-7 Structure
  • Basic information

    1. Product Name: 1-(4-tolyl)-2-(trifluoromethyl)-1H-indole
    2. Synonyms: 1-(4-tolyl)-2-(trifluoromethyl)-1H-indole
    3. CAS NO:1233881-82-7
    4. Molecular Formula:
    5. Molecular Weight: 275.273
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1233881-82-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(4-tolyl)-2-(trifluoromethyl)-1H-indole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(4-tolyl)-2-(trifluoromethyl)-1H-indole(1233881-82-7)
    11. EPA Substance Registry System: 1-(4-tolyl)-2-(trifluoromethyl)-1H-indole(1233881-82-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1233881-82-7(Hazardous Substances Data)

1233881-82-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1233881-82-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,3,8,8 and 1 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1233881-82:
(9*1)+(8*2)+(7*3)+(6*3)+(5*8)+(4*8)+(3*1)+(2*8)+(1*2)=157
157 % 10 = 7
So 1233881-82-7 is a valid CAS Registry Number.

1233881-82-7Downstream Products

1233881-82-7Relevant articles and documents

Palladium-catalyzed intramolecular aerobic C-H amination of enamines for the synthesis of 2-trifluoromethylindoles

Wei, Feng,Shen, Xiao-Qin,Chu, Jing-Jing,Hu, Bo-Lun,Zhang, Xing-Guo

, p. 720 - 725 (2018)

A new palladium-catalyzed C-H amination of aryl enamines for the synthesis of trifluoromethylated indoles is established. The attractive features of this transformation are the use of atom-economical O2 as the oxidant and easily prepared enamines as substrates. A variety of pharmaceutically important 2-trifluoromethyl indoles can be targeted in moderate to good yields with good functional compatibility.

Synthesis of 1-substituted 2-(trifluoromethyl)indoles via a palladium-catalyzed double animation reaction

Dong, Shu-Xiang,Zhang, Xing-Guo,Liu, Qiong,Tang, Ri-Yuan,Zhong, Ping,Li, Jin-Heng

experimental part, p. 1521 - 1525 (2010/10/03)

A new, selective protocol for the synthesis of 1-substituted 2-(trifluoromethyl)indoles has been developed by palladium-catalyzed double amination reaction of 2-chloro-1-(2-halophenyl)-3,3,3-trifluoroprop-1-enes with primary amines. This route allows the formation of two C-N bonds in one pot from the reaction between 2-chloro-1-(2-halophenyl)-3,3,3-trifluoroprop-1-enes and primary amines using the Pd2(dba)3/L4/t-BuONa system. Georg Thieme Verlag Stuttgart.

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