1233932-54-1

Basic information

• Product Name: C₁₅H₁₉FN₂O₃
• Synonyms: C₁₅H₁₉FN₂O₃
• CAS NO: 1233932-54-1
• Molecular Weight: 294.326
• Mol File: 1233932-54-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₉FN₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₉FN₂O₃(1233932-54-1)
• EPA Substance Registry System: C₁₅H₁₉FN₂O₃(1233932-54-1)

Safety Data

• Hazardous Substances Data: 1233932-54-1(Hazardous Substances Data)

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 845256-59-9 benzyl 3-fluoro-4-oxopiperidine-1-carboxylate 
• 141-43-5 ethanolamine 
• 1147998-34-2 phenylmethyl 4-[(trimethylsilyl)oxy]-3,6-dihydro-1(2H)-pyridinecarboxylate 

Relevant articles and documents

Discovery of spiropiperidine-based potent and selective Orexin-2 receptor antagonists

To generate novel human Orexin-2 Receptor (OX2R) antagonists, a spiropiperidine based scaffold was designed and a SAR study was carried out. Compound 4f possessed the highest OX2R antagonistic activity with an IC 50 value of 3 nM with 450-fold selectivity against Orexin-1 Receptor (OX1R).