1233933-02-2Relevant academic research and scientific papers
Exploration of a new series of CCR5 antagonists: Multi-dimensional optimization of a sub-series containing N-substituted pyrazoles
Lemoine, Remy C.,Petersen, Ann C.,Setti, Lina,Jekle, Andreas,Heilek, Gabrielle,Derosier, Andre,Ji, Changhua,Berry, Pamela,Rotstein, David M.
scheme or table, p. 4753 - 4756 (2010/10/02)
The introduction of N-substituted pyrazoles in a new series of CCR5 antagonists was shown to substantially increase antiviral activity.
Heterocyclic antiviral compounds
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Page/Page column 27-28, (2010/11/28)
Chemokine receptor antagonists, in particular, 3,7-diazabicyclo[3.3.0]octane compounds according to formula (I) wherein R1-R3 R6c and X1 are as defined herein are antagonists of chemokine CCR5 receptors which ar
