123394-75-2

Upstream product

• 123394-73-0 (4S,5R)-1,5-dimethyl-4-phenyl-3-benzyloxyacetylimidazolidin-2-one 
• 870-63-3 prenyl bromide 
• 19810-31-2 Benzyloxyacetyl chloride 
• 112791-04-5 (4R,5S)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 

Downstream Products

• 123394-80-9 (2S)-2-phenylmethoxybutane-1,4-diol 
• 123394-78-5 (R)-2-benzyloxy-5-methyl-4-hexen-1-ol 

Relevant academic research and scientific papers

ENANTIOSELECTIVE SYNTHESIS OF 2-BENZYLOXY ALCOHOLS AND 1,2-DIOLS VIA ALKYLATION OF CHIRAL GLYCOLATE IMIDES. A CONVENIENT APPROACH TO OPTICALLY ACTIVE GLYCEROL DERIVATIVES

The alkylation of the chiral enolates of glycolate imides 2a and 2b proceedes in highly diastereoselective manner to give 2'-substituted products in good yield.Reductive cleavage with LiBH4 affords the corresponding 2-benzyloxyalcohols 3a-c and 11a-b which are successively converted to 1,2-diols in high optical purity.By this method (R)-1-propanoyloxy-2,3-propanediol 9 and (S)-1-tridecyloxy-2,3-propanediol 14, a glyceride extracted from sponges Plocamiidae, have been synthesized, starting from 2a and 2b, respectively.