1233940-52-7Relevant academic research and scientific papers
IBX-promoted domino reaction of α-hydroxy amides: A facile one-pot synthesis of isatins
Wang, Yaoling,Cheng, Xu,Zhan, Zhen,Ma, Xiaojun,Nie, Ruifang,Hai, Li,Wu, Yong
, p. 2870 - 2874 (2016)
A novel and temperature-controlled oxidation of α-hydroxy amides in the presence of IBX is described. The divergent one-pot synthesis of isatins and α-formyl amides was achieved in good to excellent yields under metal-free conditions. And these two mild methods can tolerate a variety of functional groups, and are operationally simple.
