123402-48-2

Basic information

• Product Name: 1 2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHA
• Synonyms: 1 2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHA;l-β,γ-dimyristoyl-α-cephaline, 7-nitrobenzofurazan-labeled;Phosphatidylethanolamine 14:0, NBD-labeled, N-(7-Nitro-benzofurazan-4-yl)-1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, L-β,γ-Dimyristoyl-α-cephaline, 7-nitrobenzofurazan-labeled
• CAS NO: 123402-48-2
• Molecular Formula: C39H67N4O11P
• Molecular Weight: 798.949
• Mol File: 123402-48-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 830.1°C at 760 mmHg
• Flash Point: 455.8°C
• Appearance: /
• Density: 1.151g/cm³
• Vapor Pressure: 3.32E-29mmHg at 25°C
• Refractive Index: 1.524
• Storage Temp.: −20°C
• CAS DataBase Reference: 1 2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHA(CAS DataBase Reference)
• NIST Chemistry Reference: 1 2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHA(123402-48-2)
• EPA Substance Registry System: 1 2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHA(123402-48-2)

Safety Data

• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 123402-48-2(Hazardous Substances Data)

Usage

Description

1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE) is a phospholipid molecule that consists of two myristoyl fatty acid chains attached to a glycerol backbone, along with a phosphate group and an ethanolamine group. It is a vital component of cell membranes, contributing to the maintenance of the integrity and fluidity of the lipid bilayer. DMPE also has significant applications in scientific and medical fields, including its use in drug delivery and the study of lipid-protein interactions. Furthermore, it holds potential therapeutic applications for conditions such as cancer and neurological disorders, thanks to its ability to target specific cells and deliver therapeutic agents.

Uses

Used in Pharmaceutical Applications:
DMPE is used as a component of liposomes for drug delivery, enhancing the delivery and bioavailability of various therapeutic agents.
Used in Scientific Research:
DMPE serves as a tool for studying lipid-protein interactions, providing insights into the structure and function of biological membranes.
Used in Cancer Treatment:
DMPE is used as a therapeutic agent for targeting cancer cells, potentially improving treatment outcomes for patients with various types of cancer.
Used in Neurological Disorder Treatment:
DMPE has potential applications in the treatment of neurological disorders, leveraging its ability to target specific cells and deliver therapeutic agents to affected areas.
Overall, 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine plays a crucial role in both biological and medical contexts, with a wide range of applications across different industries.

InChI:InChI=1/C39H67N4O11P/c1-3-5-7-9-11-13-15-17-19-21-23-25-36(44)50-31-33(53-37(45)26-24-22-20-18-16-14-12-10-8-6-4-2)32-52-55(48,49)51-30-29-40-34-27-28-35(43(46)47)39-38(34)41-54-42-39/h27-28,33,40H,3-26,29-32H2,1-2H3,(H,48,49)/t33-/m1/s1