1234064-41-5Relevant academic research and scientific papers
Total synthesis of the proposed structure of iriomoteolide-1a
Xie, Jun,Ma, Yuelong,Horne, David A
supporting information; experimental part, p. 4770 - 4772 (2010/09/05)
The total synthesis of the proposed structure of iriomoteolide-1a has been accomplished via a Yamaguchi esterification and ring closing metathesis sequence between the C(7)-C(23) and newly synthesized Z-alkenoic acid C(1)-C(6) fragments. The spectral data of the synthetic 1, however, is at odds with data reported for the natural product, thus bringing into question the original structural assignment.
