1234199-19-9Relevant academic research and scientific papers
Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines
Brossard, Dominique,El Kihel, La?la,Clément, Monique,Sebbahi, Walae,Khalid, Mohamed,Roussakis, Christos,Rault, Sylvain
, p. 2912 - 2918 (2010)
The novelty of this work derives from the use of nitrogenous heterocycles as building block in the synthesis of conjugate bile acid derivatives. New piperazinyl bile acid derivatives were synthesized and tested in vitro against various human cancer cells
