1234261-86-9Relevant academic research and scientific papers
Synthesis and antitumor activity of novel 2′,3′-diethanethio- 2′,3′,5′-trideoxy-5′-triazolonucleoside analogues
Yu, Jin-Lan,Wu, Qin-Pei,Zhang, Qing-Shan,Xi, Xiao-Dong,Liu, Ning-Ning,Li, Yun-Zheng,Liu, Yan-Hong,Yin, Hong-Quan
supporting information; experimental part, p. 3219 - 3222 (2010/08/20)
A series of novel 2′,3′-diethanethio-2′,3′, 5′-trideoxy-5′-triazoloribonucleosides was synthesized in excellent yields and their antitumor activity was evaluated. These nucleoside analogues with aromatic substituted triazole rings showed significantly improved activity towards a broad range of tumor cell lines and those without arene substitutes were inactive.
