123438-48-2

Upstream product

• 29973-93-1 2-(3-(benzyloxy)-4-methoxyphenyl)-2-methoxyethan-1-amine 
• 29973-92-0 2-(benzyloxy)-1-methoxy-4-(1-methoxy-2-nitroethyl) Benzene 
• 63909-29-5 3-benzyloxy-4-methoxy-β-nitrostyrene 

Downstream Products

• 190278-32-1 3,10-Bis-benzyloxy-13-(4-benzyloxy-3-methoxy-phenyl)-2,11-dimethoxy-5-oxa-6b-aza-dibenzo[a,i]fluoren-6-one 
• 97614-65-8 lamellarin D 
• 656836-79-2 14-(4-hydroxy-3-methoxyphenyl)-3,11-dihydroxy-2,12-dimethoxy-8,9-dihydro-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinolin-6-one 

Relevant academic research and scientific papers

METHOD FOR PRODUCING LAMELLARIN AND DERIVATIVE THEREOF

The present application discloses a method for producing lamellarin and a derivative thereof, which is able to greatly shorten the synthesis path of the lamellarin and the derivative thereof, and to improve the yield of the lamellarin and the derivative t

Construction of Pentacyclic Lamellarin Skeleton via Grob Reaction: Application to Total Synthesis of Lamellarins H and D

An efficient construction of phenyl-substituted coumarin-pyrrole-isoquinoline-fused pentacycle via base-promoted Grob-type coupling of 3-nitrocoumarin and papaverine in a sealed tube is reported. This reaction is further applied to the total synthesis of lamellarin H in three linear steps and lamellarin D in eight linear steps with overall yields of 31% and 14%, respectively.