1234507-75-5Relevant academic research and scientific papers
Synthesis and evaluation of some new benzothiazole derivatives as potential antimicrobial agents
Soni, Balram,Ranawat, Mahendra Singh,Sharma, Rambabu,Bhandari, Anil,Sharma, Sanjay
, p. 2938 - 2942 (2010)
As benzothiazole has proven to be good antimicrobial agent, a novel series of Schiff bases of benzothiazole derivatives were synthesized. Thus condensation of 5-[2-(1,3-benzothiazol-2-yl-amino) ethyl]-4-amino-3-mercapto-(4H)-1,2,4- triazole 5 with appropriate aromatic aldehydes afforded 5-[2-(1,3-benzothiazol- 2-yl-amino)ethyl]-4-(arylideneamino)-3-mercapto-(4H)-1,2,4-triazoles 6a-g. Structures of the synthesized compounds were elucidated on the basis of elemental analyses and spectral data. All the synthesized compounds were screened for their antimicrobial activity.
