1234549-11-1

Basic information

• Product Name: S,S'-bis(2,4,6-trimethoxybenzyl) Nα-benzyloxycarbonyl-Nε-fluorenylmethoxycarbonyl-L-lysyl-D-tryptophanyl-L-leucyl-L-dithioaspartate
• Synonyms: S,S'-bis(2,4,6-trimethoxybenzyl) Nα-benzyloxycarbonyl-Nε-fluorenylmethoxycarbonyl-L-lysyl-D-tryptophanyl-L-leucyl-L-dithioaspartate
• CAS NO: 1234549-11-1
• Molecular Weight: 1309.57
• Mol File: 1234549-11-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S,S'-bis(2,4,6-trimethoxybenzyl) Nα-benzyloxycarbonyl-Nε-fluorenylmethoxycarbonyl-L-lysyl-D-tryptophanyl-L-leucyl-L-dithioaspartate(CAS DataBase Reference)
• NIST Chemistry Reference: S,S'-bis(2,4,6-trimethoxybenzyl) Nα-benzyloxycarbonyl-Nε-fluorenylmethoxycarbonyl-L-lysyl-D-tryptophanyl-L-leucyl-L-dithioaspartate(1234549-11-1)
• EPA Substance Registry System: S,S'-bis(2,4,6-trimethoxybenzyl) Nα-benzyloxycarbonyl-Nε-fluorenylmethoxycarbonyl-L-lysyl-D-tryptophanyl-L-leucyl-L-dithioaspartate(1234549-11-1)

Safety Data

• Hazardous Substances Data: 1234549-11-1(Hazardous Substances Data)

Upstream product

• 105751-18-6 N_α-carbobenzyloxy-N_ε-9-fluorenylmethoxycarbonyl-L-lysine 

Relevant articles and documents

Cyclic peptide synthesis with thioacids

(Figure Presented) C-Terminal amino acid 9-fluorenylmethylthioesters may be carried through Boc chemistry solution phase peptide synthesis sequences. After insertion of the final residue in the form of an Fmoc carbamate, treatment with piperidine releases a seco-peptide as a C-terminal thioacid that on treatment with Sanger's reagent undergoes cyclization to a cyclic peptide. Cyclic penta- and hexapeptides have been synthesized in this manner, as has a cyclic glycopeptide. Functional group compatibility with alcohols and carboxylic acids is demonstrated.