1234560-11-2

Basic information

• Product Name: tert-butyl phenanthridine-5(6H)-carboxylate
• CAS NO: 1234560-11-2
• Molecular Weight: 281.354
• Mol File: 1234560-11-2.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl phenanthridine-5(6H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl phenanthridine-5(6H)-carboxylate(1234560-11-2)
• EPA Substance Registry System: tert-butyl phenanthridine-5(6H)-carboxylate(1234560-11-2)

Safety Data

• Hazardous Substances Data: 1234560-11-2(Hazardous Substances Data)

Upstream product

• 1234560-10-1 C₁₈H₂₀BrNO₂ 

Relevant articles and documents

Synthesis of N -arylisoindolin-1-ones via pd-catalyzed intramolecular decarbonylative coupling of N -(2-bromobenzyl)oxanilic acid phenyl esters

Ethyl and phenyl oxanilates were readily prepared from N-(2-bromobenzyl) anilines and oxalyl chloride monoethyl and monophenyl esters, respectively. It was found that the ethyl oxanilate survived in the presence of K 2CO3 in DMA at 120°C and underwent an intramolecular direct arylation using Pd(OAc)2-dppf, furnishing the 5,6-dihydrophenanthridine derivative. In contrast, the corresponding phenyl oxanilates decomposed upon exposure to K2CO3 in DMA at 120 C and were transformed into N-arylisoindolin-1-ones via Pd(OAc) 2-dppf-catalyzed intramolecular decarbonylative coupling. Except for the 4-methoxy-substituted oxanilic acid phenyl ester, other phenyl oxanilates possessing electron-withdrawing (NO2, Cl) and weak electron-donating (Me) substituents provided the N-arylisoindolin-1-ones in 43-80% yields.