1234572-97-4Relevant academic research and scientific papers
A formal total synthesis of pahnerolide A
Gowrisankar, Parthasarathy,Pujari, Sandip A.,Kaliappan, Krishna P.
, p. 5858 - 5862 (2010)
(Figure Presented) Under the sea: An efficient formal total synthesis of the marine natural product palmerolide A is reported herein, involving 24 longest linear steps. The key features of our synthesis involve a combination of Sharpless epoxidation and Shimizu reaction to construct the syn aldol moiety, a JuliaKocienski reaction to construct the diene, and ring-closing metathesis to form the macrocycle (see scheme; PG = protecting group).
