1234578-08-5Relevant articles and documents
An improved practical Pd/C-catalyzed Sonogashira cross-coupling reaction for the synthesis of liquid crystals of trans-cyclohexyltolans
Shang, Hongyong,Hua, Ruimao,Zhenga, Qingwei,Zhangb, Jianli,Liang, Xiao,Zhu, Qiming
, p. 473 - 476 (2010)
An improved practical synthesis of liquid crystals of trans- cyclohexyltolans by Sonogashira cross-coupling reaction of 1-iodo- 4-(trans-4-alkylcyclohexyl)benzene with aromatic terminal alkynes in the presence of Pd/C (palladium on activated carbon) as low as 0.03mol% of Pd and CuI (2mol%) in amixture solvent of acetone-water (5 : 2 in volume) is described. The liquid crystals could be obtained in high yields as a solid with excellent purity by simple filtration, and the filtrate could be reused several times while still retaining high catalytic activity. Copyright