1234616-53-5

Upstream product

• 1246223-36-8 C₁₁H₁₃N₃O₂S 
• 853058-42-1 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ethyl ester 
• 74-88-4 methyl iodide 

Downstream Products

• 1269667-53-9 N-(3-(N-benzylpropylsulfonamido)-2,6-difluorophenyl)-4-chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide 
• 1269667-54-0 4-amino-N-(3-(N-benzylpropylsulfonamido)-2,6-difluorophenyl)-5-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide 
• 1269666-14-9 4-ethylthieno[3,2-d]pyrimidine-7-carboxylic acid [2,6-difluoro-3-(propane-1-sulfonylamino)phenyl]amide 

Relevant academic research and scientific papers

RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or trea

The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride

A facile one-step transformation of methylsulfanyl and arylsulfanyl groups on pyrimidine ring system into the corresponding chloride group was achieved using sulfuryl chloride in acetonitrile/dichloromethane.