1234619-27-2Relevant academic research and scientific papers
Concise synthesis of reduced propionates by stereoselective reductions combined with the Kobayashi reaction
Nakamura, Tatsuya,Harachi, Mio,Kano, Takaaki,Mukaeda, Yuki,Hosokawa, Seijiro
, p. 3170 - 3173 (2013)
A concise and straightforward synthesis of 2,4,6-trimethyloctanoates was established by using the sequence of the vinylogous Mukaiyama aldol reaction and regio- and stereoselective reduction reactions. All isomers were obtained selectively in a few steps. The short step synthesis of septoriamycin A, an antimalarial and antileishmanial agent, has been achieved by this methodology.
