123466-40-0

Upstream product

• 536-74-3 phenylacetylene 
• 79069-32-2 phenyl(phenylethynyl)iodonium tosylate 
• 932-88-7 1-iodo-2-phenylethyne 
• 2904-57-6 mesitylenecarbonitrile oxide 
• 123466-32-0 (phenyl)[5-phenyl-3-(2,4,6-trimethylphenyl)isoxazol-4-yl]iodonium tosylate 
• 123466-39-7 3-mesityl-5-phenylisoxazol-4-yl(phenyl)iodonium iodide 
• 148-18-5 sodium N,N-diethyldithiocarbamate 

Downstream Products

• 2904-74-7 5-phenyl-3-(2,4,6-trimethyl-phenyl)-isoxazole 

Relevant academic research and scientific papers

An alkynyliodide cycloaddition strategy for the construction of iodoisoxazoles

(Figure presented) The thermally promoted cycloaddition between alkynyliodides and nitrile oxides is reported. The process offers excellent regioselectivity and a broad scope with respect to both the iodoalkynes and chloro-oximes. Further functionalization of the highly decorated iodoisoxazole motifs can be achieved via Suzuki cross-coupling.

Reactivity of Arylethynyl(phenyl)iodonium Salts Towards some 1,3-Dipoles. X-Ray Molecular Structure of 3-Mesityl-5-phenylisoxazol-4-yl(phenyl)iodonium Toluene-p-sulphonate

Three arylethynyl(phenyl)iodonium salts reacted as 1,3-dipolarophiles with two nitrile oxides to afford phenyl(substituted isoxazolyl)iodonium salts; these gave iodoisoxazoles on reaction with nucleophiles.Phenyl(phenylethynyl)iodonium toluene-p-sulphonate reacted in the same way with nitrones but the resulting phenyl(substituted isoxazolinyl)iodonium salts, with one exeption, were difficult to isolate because of ready hydrolysis.The crystal structure of 3-mesityl-5-phenylisoxazol-4-yl(phenyl)iodonium toluene-p-sulphonate has been determined.