1234693-07-2Relevant academic research and scientific papers
Stereoselective synthesis of β-proline derivatives from allylamines via domino hydroformylation/wittig olefination and aza-michael addition
Farwick, Andreas,Heimchen, Guenter
experimental part, p. 1023 - 1032 (2010/06/17)
Under appropriate reaction conditions, a domino hydroformylation/Wittig olefination can be accomplished with derivatives of allylamines and stabilized Wittig ylides. A further highly diastereoselective aza-Michael reaction yields β-proline derivatives. These are, for example, useful as building blocks for alkaloid syntheses.
