1234786-57-2Relevant academic research and scientific papers
A straightforward preparation of aminoglycoside-dinucleotide and -diPNA conjugates via click ligation assisted by microwaves
Alguacil, Javier,Defaus, Sira,Claudio, Ana,Trapote, Alejandro,Masides, Marta,Robles, Jordi
experimental part, p. 3102 - 3109 (2010/08/19)
An alternative and straightforward method to prepare aminoglycoside- dinucleotide and -diPNA conjugates is reported, which is based, on copper-catalyzed Huisgen azidealkyne cycloaddition (click chemistry ligation) assisted by microwave irradiation. This method permitted conjugations to be performed in aqueous solution, in very short times and with readily prepared, precursors.
