1235035-60-5

Upstream product

• 1235035-59-2 9-isopropyl-6-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)-9H-purine 

Downstream Products

• 1535484-33-3 N₁,N₃-bis[3,5-bis(trifluoromethyl)phenyl]-5-hydroxy-2-(9-isopropyl-9H-purin-6-yl)benzene-1,3-diamine 
• 1535484-32-2 N-[3,5-bis(trifluoromethyl)phenyl]-5-hydroxy-2-(9-isopropyl-9H-purin-6-yl)aniline 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

In one aspect, the present invention provides for a compound of Formula I; in which the variable X1a, X1b, X1c, X1d, Q, A, R1, B, L, E, and the subscripts m and n have the meanings as described herein. In another aspect, the present invention provides for pharmaceutical compositions comprising compounds of Formula I as well as methods for using compounds of Formula I for the treatment of diseases and conditions (e.g., cancer, thrombocythemia, etc) characterized by the expression or over-expression of Bcl-2 anti-apoptotic proteins, e.g., of anti-apoptotic Bcl-xL proteins.