123530-44-9Relevant academic research and scientific papers
Unexpected chain-terminating side reaction caused by histidine and acetic anhydride in solid-phase peptide synthesis.
Ishiguro,Eguchi
, p. 506 - 508 (2007/10/02)
Capping is a useful technique to facilitate purification of a crude deprotected peptide in solid-phase peptide synthesis. However, we observed a serious side reaction caused by the Ac2O capping procedure, when it was applied to a synthesis of a peptide containing His. The mechanism of the side reaction was studied.
