123530-64-3Relevant academic research and scientific papers
DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF
-
Paragraph 0511; 0514-0515, (2020/12/13)
The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3-dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to a pharmaceutical composition and formulation containing a derivative of piperlongumine; and use of the derivatives and analogs for treating cancer, reducing inflammation and/or treating an autoimmune or inflammatory disease.
DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF
-
Page/Page column 117; 118; 119, (2019/06/11)
The present invention relates to a group of 1-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2,3- dihydropyridin-6-one (piperlongumine) derivatives, analogs and pharmaceutically acceptable salts thereof. The present invention also relates to processes for preparing the same; a pharmaceutical composition and formulation containing a derivative of piperlogumine; and use of the derivatives and analogs for treating cancer.
Pyridazines.LI. On the Reactivity of Pyridazinecarbaldehydes towards Selected Active-Hydrogen Compounds
Dostal, Wolfgang,Heinisch, Gottfried,Holzer, Wolfgang,Perhauc, Ingrid,Zheng, Changtu
, p. 1313 - 1321 (2007/10/02)
Reactions of 3-pyridazinecarbaldehyde and 3-pyridazinecarbaldehyde with various active methylene carbanions were studied.The products obtained in Knoevenagel reactions, Wittig-Horner-Emmons reactions, and Hantzsch-type reactions are presented.
