1235374-44-3 Usage
Uses
Used in Pharmaceutical Industry:
4-Amino-7-bromomidazo[2,1-f][1,2,4]triazine is used as a key intermediate in the synthesis of various pharmaceutical compounds due to its unique chemical structure and reactivity. Its potential as an antiviral and anticancer agent makes it a valuable component in the development of new therapeutics.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Amino-7-bromomidazo[2,1-f][1,2,4]triazine serves as a building block for the creation of agrochemical products. Its incorporation into these products can enhance their effectiveness in protecting crops from pests and diseases.
Used as an Antiviral Agent:
4-Amino-7-bromomidazo[2,1-f][1,2,4]triazine is utilized as an antiviral agent for its potential to inhibit viral replication and reduce the severity of viral infections.
Used as an Anticancer Agent:
4-AMino-7-broMoiMidazo[2,1-f][1,2,4]triazine is employed as an anticancer agent, where it may contribute to the inhibition of cancer cell growth and the disruption of cancer-related pathways, offering a potential therapeutic option for cancer treatment.
Used as a Protein Kinase Inhibitor:
4-Amino-7-bromomidazo[2,1-f][1,2,4]triazine is used in research and development as a protein kinase inhibitor, which can play a crucial role in regulating cellular processes and may have implications for the treatment of various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1235374-44-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,5,3,7 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1235374-44:
(9*1)+(8*2)+(7*3)+(6*5)+(5*3)+(4*7)+(3*4)+(2*4)+(1*4)=143
143 % 10 = 3
So 1235374-44-3 is a valid CAS Registry Number.
1235374-44-3Relevant academic research and scientific papers
A process for preparing 7-bromo imidazo [2,1-f] [1, 2, 4] triazin-4-amine method
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Paragraph 0031-0033, (2016/11/24)
The invention discloses a method for preparing 7-bromoimidazo[2,1-f][1,2,4]triazin-4-amine. According to the invention, a compound IX is adopted as a a raw material, and is subjected to a reaction with a compound X under the effect of alkali, such that a
Synthesis and biochemical testing of 3-(carboxyphenylethyl)imidazo[2,1-f] [1,2,4]triazines as inhibitors of AMP deaminase
Lindell, Stephen D.,Maechling, Simon,Sabina, Richard L.
scheme or table, p. 286 - 289 (2010/10/20)
C-Ribosyl imidazo[2,1-f][1,2,4]triazines and 3-[2-(3-carboxyphenyl)ethyl]- 3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ols represent two classes of known AMP deaminase inhibitors. A combination of the aglycone from the former class with the ribose phosphate mimic from the latter led to the 3-[2-(3-carboxyphenyl)ethyl]imidazo[2,1-f][1,2,4]triazines, which represent a new class of AMP deaminase inhibitors. The best compound, 3-[2-(3-carboxy-5,6,7, 8-tetrahydronaphthyl)ethyl]imidazo[2,1-f][1,2,4]triazine (8), was a good inhibitor of all three human AMPD recombinant isozymes (AMPD1, AMPD2, and AMPD3; IC50 = 0.9-5.7 μM) but a poor inhibitor of the plant recombinant enzyme (Arabidopsis FAC1; IC50 = 200 μM).
