1235453-07-2Relevant academic research and scientific papers
Efficient synthesis of nicotianamine and non-natural analogues
Bouazaoui, M'Barek,Larrouy, Manuel,Martinez, Jean,Cavelier, Florine
experimental part, p. 6609 - 6617 (2011/02/25)
An efficient synthesis of nicotianamine has been achieved by using a new strategy based on N-alkylation. Sulfonamide activation proved to be necessary for the alkylation of the primary amine and the 2-(trimethylsilyl)ethanesulfonyl group was easily introd
Determination of the structure and its absolute configuration of 2″-hydroxynicotianamine, an inhibitor against Angiotensin-I converting enzyme in buckwheat, through the total synthesis
Yoshikawa, Keisuke,Watanabe, Hidenori,Aoyagi, Yasuo,Kitahara, Takeshi
experimental part, p. 1435 - 1444 (2011/01/12)
Nicotianamine is known as an inhibitor against Angiotensin-I Converting Enzyme (ACE). We synthesized a new nicotianamine derivative with an additional hydroxy group isolated from buckwheat (Fagopyrum esculentum Moench) powder and determined its regio and stereochemistry unambiguously by the enantioselective synthesis of diastereomers.
