1235454-46-2Relevant academic research and scientific papers
Copper(I)-catalyzed synthesis of novel 4-(trifluoromethyl)-[1,2,3] triazolo[1,5-a]quinoxalines via cascade reactions of N-(o-haloaryl)alkynylimine with sodium azide
Chen, Zixian,Zhu, Jiangtao,Xie, Haibo,Li, Shan,Wu, Yongming,Gong, Yuefa
supporting information; experimental part, p. 1296 - 1300 (2010/07/03)
Novel tricyclic 4-(trifluoromethyl)[1, 2, 3]triazolo[1,5-a]quinoxalines were readily prepared from N-(o-haloaryl)alkynylimines and sodium azide via copper(I)-catalyzed tandem reactions. This synthetic strategy provides an efficient way to access a library of novel heterocyclic compounds that are of interest in drug discovery.
A Novel method for the synthesis of 2-trifluoromethylindoles from N -(o -Haloaryl)alkynylimines
Chen, Zixian,Zhu, Jiangtao,Xie, Haibo,Li, Shan,Wu, Yongming,Gong, Yuefa
supporting information; experimental part, p. 1418 - 1420 (2010/07/14)
Treatment of various types of N-(o-haloaryl)-alkynylimines in the presence of Pd(PPh3)2Cl2 gave 2-trifluoromethylindoles in high yields. This approach provides a novel and facile access to the biologically important fluorine-containing indole derivatives.
