1235488-50-2 Usage
Uses
Used in Emergency Medicine:
Flumazenil is used as a specific antidote for benzodiazepine overdose, helping to rapidly reverse the central nervous system depression caused by excessive benzodiazepine consumption. Its quick action and specificity for benzodiazepine receptors make it an essential tool in emergency situations where rapid reversal of benzodiazepine effects is crucial.
Used in Anesthesia:
In the field of anesthesia, flumazenil is utilized to reverse the effects of benzodiazepines used for sedation during surgery. By binding to the benzodiazepine receptors, it effectively counteracts the sedative and hypnotic effects, allowing patients to regain consciousness more quickly and with fewer residual effects post-surgery.
Used in Diagnostic Medicine:
Flumazenil can also be employed in diagnostic medicine to differentiate between causes of reduced consciousness, such as benzodiazepine overdose and other central nervous system depressant intoxications. Its ability to reverse benzodiazepine effects can help clinicians determine the underlying cause of a patient's condition and guide appropriate treatment.
Used in Research:
In research settings, flumazenil serves as a valuable tool for studying the role of benzodiazepines and the GABA receptor complex in various physiological and pathological processes. Its antagonistic properties allow researchers to investigate the effects of benzodiazepine receptor activation and inhibition, contributing to a deeper understanding of the mechanisms underlying benzodiazepine action and potential therapeutic applications.
Overall, N-(5-Acetyl-2-fluorophenyl)-N-methylacetamide, or flumazenil, is a versatile compound with significant applications in medicine, particularly in emergency situations, anesthesia, diagnostic medicine, and research. Its ability to reverse the effects of benzodiazepines and its relative safety and tolerability make it an indispensable asset in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 1235488-50-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,5,4,8 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1235488-50:
(9*1)+(8*2)+(7*3)+(6*5)+(5*4)+(4*8)+(3*8)+(2*5)+(1*0)=162
162 % 10 = 2
So 1235488-50-2 is a valid CAS Registry Number.
1235488-50-2Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE
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Page/Page column 4, (2011/11/13)
The present invention relates to a new process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluorophenyl]-N-methyl-acetamide (I) in a high yield and high purity, which is an intermediate in the synthesis of compounds with affinity for GABAsub
PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE
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Page/Page column 10-11, (2010/08/08)
The present invention relates to a new process for the preparation of N-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-N-methyl-acetamide (I) in a high yield and high purity, which is an intermediate in the synthesis of compounds with affinity for GABAA r
