1235563-41-3

Upstream product

• 85-44-9 phthalic anhydride 
• 126-81-8 dimedone 
• 620-23-5 m-tolyl aldehyde 
• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 

Relevant academic research and scientific papers

An efficient and green one-pot synthesis of indazolo[1,2-b]-phthalazinetriones via three-component reaction of aldehydes, dimedone, and phthalhydrazide using Fe3O4@SiO2 core-shell nanoparticles

An efficient and eco-friendly procedure for the one-pot synthesis of biologically active heterocyclic compounds including indazolo[1,2-b]-phthalazinetriones has been developed in the presence of Fe3O4@SiO2 nanoparticles. T

Synthesis of phthalazine compounds using heterogeneous base catalyst based on silica nanoparticles obtained from rice husk

In this study, the nanoparticles of amorphous silica were easily extracted from low-cost rice husk ash. They were functionalized with 3-(chloropropyl) trimethoxysilane by incorporating chloropropyl groups directly through the condensation of nanosilica an

Deep eutectic solvent an efficient reaction medium for the synthesis of chromeno pyrazolo and indazolo phthalazine derivatives

The volatile, harmful and hazardous solvents have impact on human health, all organisms and environment. To reduce the use of hazardous volatile solvents, there is need to develop the alternative green reaction medium for organic transformations and is th

Phospho sulfonic acid: A novel and efficient solid acid catalyst for the one-pot preparation of indazolo[1,2-b]-phthalazinetriones

An efficient one-pot condensation of aldehyde, dimedone and phthalhydrazide has been achieved in the presence of a catalytic amount of phospho sulfonic acid as a novel environmentally benign heterogeneous solid acid under solvent-free conditions. Diverse

Fe3O4@silica sulfuric acid nanoparticles: An efficient reusable nanomagnetic catalyst as potent solid acid for one-pot solvent-free synthesis of indazolo[2,1-b]phthalazine-triones and pyrazolo[1,2-b]phthalazine-diones

Regarding the green chemistry's goals, silica-coated magnetite nanoparticles (MNPs) open up new avenue to introduce an amazing and efficient system for facilitating catalyst recovery in different organic reactions. Therefore, in this paper the preparation

A rapid, one-pot, four-component route to 2H-indazolo[2,1-b]phthalazine- triones

A new, efficient, and environmentally benign protocol for the one-pot, four-component synthesis of 2,2-dimethyl-13-phenyl-2,3-dihydro-1H-indazolo[2,1- b]phthalazine-1,6,11(13H)-trione by condensation of phthalic anhydride, hydrazinium hydroxide, aromatic aldehydes, and dimedone catalyzed by Ce(SO 4)2·4H2O as an ecofriendly catalyst with high catalytic activity and reusability at 125 °C under solvent-free conditions is reported. The reaction proceeds to completion within 5-10 min in 71-95% yield. To the best of our knowledge, this new procedure provides the first example of an efficient synthetic method for 2H-indazolo[2,1-b] phthalazine-1,6,11(13H)-trione via a four-component reaction.

Highly efficient three-component synthesis of 1H-indazolo[1,2-b] phthalazinetrione derivatives catalyzed by heteropolyacids

Efficient one-pot condensation of aldehyde, dimedone, and phthalhydrazide has been achieved in the presence of a catalytic amount of tungstosilicic acid under solvent-free conditions. A variety of 1H-indazolo[1,2-b]phthalazinetrione derivatives were prepa