1235866-62-2Relevant academic research and scientific papers
The pthaladyns: GTP competitive inhibitors of dynamin I and II GTPase derived from virtual screening
Odell, Luke R.,Howan, Dian,Gordon, Christopher P.,Robertson, Mark J.,Chau, Ngoc,Mariana, Anna,Whiting, Ainslie E.,Abagyan, Ruben,Daniel, James A.,Gorgani, Nick N.,Robinson, Phillip J.,McCluskey, Adam
, p. 5267 - 5280 (2010)
We report the development of a homology model for the GTP binding domain of human dynamin I based on the corresponding crystal structure of Dictyostelium discoidum dynamin A. Virtual screening identified 2-[(2-biphenyl-2-yl-1,3-dioxo- 2,3-dihydro-1H-isoin
