123594-04-7

Basic information

• Product Name: 4-CHLOROISOINDOLINE
• Synonyms: 4-CHLOROISOINDOLINE;1H-Isoindole,4-chloro-2,3-dihydro-)
• CAS NO: 123594-04-7
• Molecular Formula: C₈H₈ClN
• Molecular Weight: 153.61
• Mol File: 123594-04-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 246.6°C at 760 mmHg
• Flash Point: 102.9°C
• Appearance: /
• Density: 1.214g/cm³
• Vapor Pressure: 0.0269mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: 2-8°C
• PKA: 8.11±0.20(Predicted)
• CAS DataBase Reference: 4-CHLOROISOINDOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROISOINDOLINE(123594-04-7)
• EPA Substance Registry System: 4-CHLOROISOINDOLINE(123594-04-7)

Safety Data

• Hazardous Substances Data: 123594-04-7(Hazardous Substances Data)

Usage

General Description

4-Chloroisoindoline is a chemical compound with the molecular formula C8H6ClNO. It is a chlorinated isoindoline derivative that is commonly used in the pharmaceutical industry as a building block for the synthesis of various drug molecules. Its structure consists of a five-membered ring containing a chlorine atom and a nitrogen atom, making it a heterocyclic compound. 4-CHLOROISOINDOLINE has been found to possess interesting biological activities and is utilized as a versatile intermediate in the development of new drugs due to its unique structural properties. Additionally, it is also used as a reagent in organic synthesis and medicinal chemistry for the preparation of bioactive molecules.

InChI:InChI=1/C8H8ClN/c9-8-3-1-2-6-4-10-5-7(6)8/h1-3,10H,4-5H2

Upstream product

• 7147-90-2 4-chlorophthalimide 
• 51108-30-6 4-chloro-1H-isoindole-1,3(2H)-dione 

Relevant articles and documents

HCV NS3 protease inhibitors

The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.

Isoindoline derivative

Isoindoline derivatives represented by the formula (I) and their salts are disclosed. STR1 There are many varieties for the compound depending on the types of residues R1 -R9 and X. The compounds can be prepared from quinoline derivatives of the formula (II) and an isoindoline derivatives of the formula (III). The compounds of formula (I) and their salts have excellent antibacterial activities against both gram positive and gram negative microorganisms. They can be used as a medicine, an agrichemical, and a food preservative.