1235968-11-2Relevant academic research and scientific papers
A new method for the stereoselective construction of angular methyl group of fuzed cyclic ethers
Kadota, Isao,Kishi, Takayuki,Fujisawa, Yuka,Yamagami, Yuji,Takamura, Hiroyoshi
, p. 3960 - 3961 (2010)
A convenient method for the stereoselective construction of angular methyl group of fuzed cyclic ethers is described. Reactions of mixed thioacetals with Me2Zn/Zn(OTf)2 afforded the corresponding methylated products in good yields. Various protective groups such as MOM ether, benzylidene acetal, TBS ether, and pivaloyl group were stable under the reaction conditions.
