1236003-09-0

Basic information

• Product Name: N₂-(1-benzyl-1H-benzo[d]imidazol-2-yl)-N₄-(3-fluorophenyl)pyrimidine-2,4-diamine
• Synonyms: N₂-(1-benzyl-1H-benzo[d]imidazol-2-yl)-N₄-(3-fluorophenyl)pyrimidine-2,4-diamine
• CAS NO: 1236003-09-0
• Molecular Weight: 410.453
• Mol File: 1236003-09-0.mol

Chemical Properties

• CAS DataBase Reference: N₂-(1-benzyl-1H-benzo[d]imidazol-2-yl)-N₄-(3-fluorophenyl)pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N₂-(1-benzyl-1H-benzo[d]imidazol-2-yl)-N₄-(3-fluorophenyl)pyrimidine-2,4-diamine(1236003-09-0)
• EPA Substance Registry System: N₂-(1-benzyl-1H-benzo[d]imidazol-2-yl)-N₄-(3-fluorophenyl)pyrimidine-2,4-diamine(1236003-09-0)

Safety Data

• Hazardous Substances Data: 1236003-09-0(Hazardous Substances Data)

Upstream product

• 898805-58-8 2-chloro-N-(3-fluorophenyl)pyrimidin-4-amine 
• 43182-10-1 2-amino-1-benzylbenzimidazole 

Relevant articles and documents

Convenient preparation of 4-aryl-2-(heteroarylamino)pyrimidines and 4-anilino-2-(heteroarylamino)pyrimidines

4-Aryl-2-anilinopyrimidines and 2,4-dianilinopyrimidines are privileged structures found in many drug-like molecules and biologically active compounds. A method for the quick assembly of novel 4-aryl- and 4-anilino-2-(heteroarylamino)pyrimidines via Buchwald-Hartwig N-arylations at elevated temperatures under sealed tube conditions is reported. This method's convenience and practicality is demonstrated through the preparation of several novel non-nucleoside reverse transcriptase inhibitor (NNRTI) analogues.