1236122-77-2

Upstream product

• 41988-26-5 7-(2-bromoethoxy)-5-hydroxy-2-phenyl-4H-chromen-4-one 
• 75-31-0 isopropylamine 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 33495-30-6 2-benzoyloxy-4,6-dimethoxyacetophenone 
• 33507-94-7 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylpropane-1,3-dione 
• 21392-57-4 Dimethyl-chrysin 

Relevant academic research and scientific papers

Synthesis and cytotoxicity of novel chrysin derivatives

A series of chrysin derivatives 8a-8v were prepared and tested in vitro against HCT-116 (human colon cancer cell line), Hela (human cervical carcinoma cell line), DU-145 (human prostate cell line), K562 (human leukemia cell line), and SGC-7901 (human gastric cancer cell line). The chemical structures of these compounds were confirmed by means of MS, IR, 1H NMR, 13C NMR, and elemental analysis. Among these derivatives, 7-(2-(piperazin-1- yl)ethoxy)-5-hydroxy-2-phenyl-4H-chromen-4-one, 8n, had the strongest activity against HCT-116, Hela, DU-145, K562, and SGC-7901 cells. Springer Science+Business Media, LLC 2010.