1236123-75-3Relevant academic research and scientific papers
Enantioselective (Formal) Aza-diels-alder reactions with non-danishefsky-type dienes
Tambar, Uttam K.,Lee, Sharon K.,Leighton, James L.
supporting information; scheme or table, p. 10248 - 10250 (2010/09/05)
Enantioselective (formal) aza-Diels-Alder reactions between acylhydrazones and non-Danishefsky-type dienes have been developed. The reactions are promoted by a simple and economical chiral silicon Lewis acid and are typically conducted at ambient temperature. Both glyoxylate- and aliphatic aldehyde-derived hydrazones may be employed, as may variously substituted dienes, leading to the synthesis of a diverse array of tetrahydropyridines with good to excellent levels of enantioselectivity.
